ARGEOS: A New Bioinformatic Tool for Detailed Systematics Search in GEO and ArrayExpress.

ABSTRACT: Conduct a reanalysis of transcriptome data for studying intracellular signaling or solving other experimental problems is becoming increasingly popular. Gene expression data are archived as microarray or RNA-seq datasets mainly in two public databases: Gene Expression Omnibus (GEO) and ArrayExpress (AE). These databases were not initially intended to systematically search datasets, making it challenging to conduct a secondary study. Therefore, we have created the ARGEOS service, which has the following advantages that facilitate the search: (1) Users can simultaneously send several requests that are supposed to be used for systematic searches, and it is possible to correct the requests; (2) advanced analysis of information about the dataset is available. The service collects detailed proto

SUBMITTER: Gavrish GE 

PROVIDER: S-EPMC8533512 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature