Children with Intestinal Failure Maintain Their Renal Function on Long-Term Parenteral Nutrition.

ABSTRACT:

Background

Long-term parenteral nutrition (PN) has been associated with renal complications, including hypercalciuria, nephrocalcinosis, proteinuria and reduced glomerular filtration rate (GFR). Pediatric data are scarce and mostly short-term. Our study aimed to evaluate renal complications in children with intestinal failure (IF) receiving long-term PN.

Methods

A cross-sectional study was performed in a tertiary pediatric IF clinic of patients receiving home-PN treatment for more than 1 year. Data regarding medical background, anthropometrics, laboratory investigations and abdominal sonography were retrieved.

Results

Complete data were available for 15 children (67% males), with a median age of 6 (range 1.5-15) years and a median (IQR) PN duration of 4 (1.5-6) years.

SUBMITTER: Guz Mark A 

PROVIDER: S-EPMC8539167 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature