COVID-19 and Cancer: Discovery of Difference in Clinical Immune Indexes.

ABSTRACT:

Objective

This study explored the consistency and differences in the immune cells and cytokines between patients with COVID-19 or cancer. We further analyzed the correlations between the acute inflammation and cancer-related immune disorder.

Methods

This retrospective study involved 167 COVID-19 patients and 218 cancer patients. COVID-19 and cancer were each further divided into two subgroups. Quantitative and qualitative variables were measured by one-way ANOVA and chi-square test, respectively. Herein, we carried out a correlation analysis between immune cells and cytokines and used receiver operating characteristic (ROC) curves to discover the optimal diagnostic index.

Results

COVID-19 and cancers were associated with lymphopenia and high levels of monocytes, neutr

SUBMITTER: Zeng X 

PROVIDER: S-EPMC8546403 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature