Etiology of Diarrhea Requiring Hospitalization in Bangladesh by Quantitative Polymerase Chain Reaction, 2014-2018.

ABSTRACT:

Background

Diarrhea remains a major public health problem and characterization of its etiology is needed to prioritize interventions. However, most data are from single-site studies of children. We tested samples from participants of any age from 11 geographically diverse hospitals in Bangladesh to describe pathogen-specific burdens of diarrhea.

Methods

We utilized 2 existing diarrhea surveillance systems: a Nationwide network at 10 sentinel hospitals and at the icddr,b hospital. We tested stools from enrolled participants and nondiarrheal controls for enteropathogens using quantitative polymerase chain reaction and calculated pathogen-specific attributable fractions (AFs) of diarrhea.

Results

We analyzed 5516 patients with diarrhea and 735 controls. Overall, rotaviru

SUBMITTER: Taniuchi M 

PROVIDER: S-EPMC8563176 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature