Self-Therapeutic Cobalt Hydroxide Nanosheets (Co(OH)₂ NS) for Ovarian Cancer Therapy.

ABSTRACT: High-grade serous ovarian cancer (HGSOC) is one of the major life-threatening cancers in women, with a survival rate of less than 50%. So far, chemotherapy is the main therapeutic tool to cure this lethal disease; however, in many cases, it fails to cure HGSOC even with severe side effects. Self-therapeutic nanomaterials could be an effective alternative to chemotherapy, facilitated by their diverse physicochemical properties and the ability to generate reactive species for killing cancer cells. Herein, inorganic cobalt hydroxide nanosheets (Co(OH)₂ NS) were synthesized by a simple solution process at room temperature, and morphological, spectroscopic, and crystallographic analyses revealed the formation of Co(OH)₂ NS with good crystallinity and purity. The as-prepare

SUBMITTER: Adeel M 

PROVIDER: S-EPMC8567285 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature