Dataset Information
Development of at-home sample collection logistics for large-scale seroprevalence studies.
Ontology highlight
ABSTRACT: Background
Serological studies rely on the recruitment of representative cohorts; however, such efforts are specially complicated by the conditions surrounding the COVID19 pandemic.Methods
We aimed to design and implement a fully remote methodology for conducting safe serological surveys that also allow for the engagement of representative study populations.Results
This design was well-received and effective. 2,066 participants ≥18 years old were enrolled, reflecting the ethnic and racial composition of Massachusetts. >70% of them reported being satisfied/extremely satisfied with the online enrollment and at-home self-collection of blood samples. While 18.6% reported some discomfort experienced with the collection process, 72.2% stated that they would be willing to test weekly if enrolled in a long-term study.Conclusions
High engagement and positive feedback from participants, as well as the quality of self-collected specimens, point to the usefulness of this fully remote, self-collection-based study design for future safer and efficient population-level serological surveys.
SUBMITTER: Aatresh AV
PROVIDER: S-EPMC8568136 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Publications
Development of at-home sample collection logistics for large-scale seroprevalence studies.
PloS one 20211104 11
<h4>Background</h4>Serological studies rely on the recruitment of representative cohorts; however, such efforts are specially complicated by the conditions surrounding the COVID19 pandemic.<h4>Methods</h4>We aimed to design and implement a fully remote methodology for conducting safe serological surveys that also allow for the engagement of representative study populations.<h4>Results</h4>This design was well-received and effective. 2,066 participants ≥18 years old were enrolled, reflecting the ...[more]
