The association of glucose metabolism and kidney function in middle-aged adults.

ABSTRACT:

Background

Previous clinical studies have shown that various measures of glucose metabolism are associated with a risk of chronic kidney disease in different populations, but results were not consistent. In this study we assessed measures of glucose metabolism and their association with kidney function in a population-based study.

Methods

The Netherlands Epidemiology of Obesity study is a population-based cohort study of middle-aged men and women. We categorized the study population according to glycaemic levels into normoglycaemia (reference group), pre-diabetes mellitus (pre-DM), known DM and newly diagnosed DM. Outcome variables were serum creatinine, estimated glomerular filtration rate (eGFR), glomerular hyperfiltration (defined as an eGFR >90th percentile; >102 mL/min/

SUBMITTER: Schroijen MA 

PROVIDER: S-EPMC8572983 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature