Development and validation of prognostic scoring in primary intestinal diffuse large B-cell lymphoma: a single-institution study of 184 patients.

ABSTRACT:

Background

The incidence of primary intestinal diffuse large B-cell lymphoma (PI-DLBCL) is much lower than primary gastric DLBCL, and large-scale analyses on the clinical characteristics, molecular features, therapeutic strategies, and risk stratification have been seldomly performed in PI-DLBCL.

Methods

To assess prognostic model development, 107 PI-DLBCL patients diagnosed before 2014 were studied for prognosis factors including different primary involved sites and treatment strategies. For internal validation, a non-random split sample set with 77 PI-DLBCL patients after 2014 was included for validation of the prognosis factors.

Results

Patients with an ileocecal lesion presented with better survival time than those with non-ileocecal sites, with surgical resection

SUBMITTER: Fan X 

PROVIDER: S-EPMC8576653 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature