Development and validation of a survival nomogram in patients with primary testicular diffuse large B-cell lymphoma.

ABSTRACT:

Objective

We developed and validated a nomogram for overall survival (OS) and cancer-specific survival (CSS) prediction in patients with primary testicular diffuse large B-cell lymphoma (PT-DLBCL).

Methods

Patients diagnosed with PT-DLBCL were selected from the Surveillance, Epidemiology, and End Results (SEER) database. Independent prognostic factors were analyzed to establish a nomogram of OS and CSS. Patients were reclassified into high- and low-risk groups; survival was compared using Kaplan-Meier curves and log-rank tests.

Results

We collected 1099 PT-DLBCL cases (2000-2019) from SEER and randomized into training (n = 771) and validation (n = 328) cohorts. In univariate and multivariate Cox regression analyses, five prognostic indicators (age, treatment modality,

SUBMITTER: Zhi Y 

PROVIDER: S-EPMC10492492 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature