Trait correlated expression combined with eQTL and ASE analyses identified novel candidate genes affecting intramuscular fat.

ABSTRACT:

Background

Intramuscular fat (IMF) content is a determining factor for meat taste. The Luchuan pig is a fat-type local breed in southern China that is famous for its desirable meat quality due to high IMF, however, the crossbred offspring of Luchuan sows and Duroc boars displayed within-population variation on meat quality, and the reason remains unknown.

Results

In the present study, we identified 212 IMF-correlated genes (FDR ≤ 0.01) using correlation analysis between gene expression level and the value of IMF content. The IMF-correlated genes were significantly enriched in the processes of lipid metabolism and mitochondrial energy metabolism, as well as the AMPK/PPAR signaling pathway. From the IMF-correlated genes, we identified 99 genes associated with expression quanti

SUBMITTER: Liu Y 

PROVIDER: S-EPMC8577010 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature