Antihypertensive treatments and risks of lung Cancer: a large population-based cohort study in Hong Kong.

ABSTRACT:

Background

There is a growing concern that the use of anti-hypertensives may be associated with an increased risk of cancer, but it remains uncertain for the association between anti-hypertensives and lung cancer risk, as well as their interaction with aspirin in chemoprotective effects.

Methods

The goal of this study is to assess the association between anti-hypertensives use and the risk of lung cancer, as well as the chemopreventive impacts from the combination usage of aspirin and anti-hypertensives. A retrospective cohort study was conducted based on all the public hospital electronic medical records in Hong Kong. Patients with prescription records of anti-hypertensives (ACEi/ARB, CCB, β-blocker,α-blocker) and/or aspirin were included as the exposure groups. Using the C

SUBMITTER: Li J 

PROVIDER: S-EPMC8582182 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature