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Antithrombotic therapy in patients with liver disease: population-based insights on variations in prescribing trends, adherence, persistence and impact on stroke and bleeding.


ABSTRACT:

SUBMITTER: Chang WH 

PROVIDER: S-EPMC8589727 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature

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Antithrombotic therapy in patients with liver disease: population-based insights on variations in prescribing trends, adherence, persistence and impact on stroke and bleeding.

Chang Wai Hoong WH   Mueller Stefanie H SH   Tan Yen Yi YY   Lai Alvina G AG  

The Lancet regional health. Europe 20210908


<h4>Background</h4>Patients with liver disease have complex haemostasis and due to such contraindications, landmark randomised controlled trials investigating antithrombotic medicines have often excluded these patients. As a result, there has been limited consensus on the safety, efficacy and monitoring practices of anticoagulant and antiplatelet therapy in patients with liver disease. This study aims to investigate prescribing prevalence, adherence, persistence and impact of adherence on bleedi  ...[more]

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