Heterogeneous immunogenicity of SARS-CoV-2 vaccines in cancer patients receiving radiotherapy.
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ABSTRACT:
SUBMITTER: Bowes CL
PROVIDER: S-EPMC8613981 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Publications
Heterogeneous immunogenicity of SARS-CoV-2 vaccines in cancer patients receiving radiotherapy.
Bowes Cynthia L CL Naranbhai Vivek V St Denis Kerri J KJ Lam Evan C EC Bertaux Brittany B Keane Florence K FK Khandekar Melin J MJ Balazs Alejandro B AB Iafrate John A JA Gainor Justin F JF Willers Henning H
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20211125
The immunogenicity of SARS-CoV-2 vaccines in cancer patients receiving radiotherapy is unknown. This prospective cohort study demonstrates that anti-SARS-CoV-2 spike antibody and neutralization titers are reduced in a subset of thoracic radiotherapy patients, possibly due to immunosuppressive conditions. Antibody testing may be useful to identify candidates for additional vaccine doses. ...[more]
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