Stability of Rosmarinic Acid and Flavonoid Glycosides in Liquid Forms of Herbal Medicinal Products-A Preliminary Study.

ABSTRACT: Peppermint leaf, sage leaf, thyme herb, and their preparations are common components of herbal medicinal products (HMPs). According to the European Pharmacopoeia guidelines, the above-mentioned plant substances are standardized for the content of essential oils, omitting polyphenols, which also have a significant impact on their activities. The aim of this study was to evaluate the stability of the predominant polyphenols-rosmarinic acid, luteolin-7-O-β-glucuronide, and eriocitrin-in selected commercial liquid HMPs containing thyme, sage, and peppermint under long-term, intermediate, and accelerated testing conditions. Qualitative and quantitative analyses of these polyphenols were performed by the previously optimized and validated HPLC-DAD method. Rosmarinic acid stability was better in

SUBMITTER: Bodalska A 

PROVIDER: S-EPMC8624675 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature