Association of Acute Kidney Injury During Diabetic Ketoacidosis With Risk of Microalbuminuria in Children With Type 1 Diabetes.

ABSTRACT:

Importance

Diabetic kidney disease is among the most important causes of end-stage kidney disease worldwide. Risk factors for diabetic kidney disease remain incompletely defined. Recent studies document a high frequency of acute kidney injury (AKI) during diabetic ketoacidosis (DKA) in children, raising the question of whether these AKI episodes might contribute to future risk of diabetic kidney disease.

Objective

To determine whether episodes of AKI occurring during DKA in children are associated with increased risk of development of microalbuminuria.

Design, setting, and participants

This retrospective review of medical records included children with type 1 diabetes with 1 or more urine albumin levels measured during routine diabetes care from 2 university-affiliate

SUBMITTER: Huang JX 

PROVIDER: S-EPMC8630664 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature