Highly Efficient Production of Heteroarene Phosphonates by Dichromatic Photoredox Catalysis.

ABSTRACT: A new strategy to achieve efficient aerobic phosphorylation of five-membered heteraroenes with excellent yields using dichromatic photoredox catalysis in a gel-based nanoreactor is described here. The procedure involves visible aerobic irradiation (cold white LEDs) of a mixture containing the heteroarene halide, trisubstituted phospite, N,N-diisopropylethylamine (DIPEA) as sacrificial agent, and catalytic amounts of 9,10-dicyanoanthracene (DCA) in the presence of an adequate gelator, which permits a faster process than at the homogeneous phase. The methodology, which operates by a consecutive photoinduced electron transfer (ConPET) mechanism, has been successfully applied to the straightforward and clean synthesis of a number of different heteroarene (furan, thiophene,

SUBMITTER: Herrera-Luna JC 

PROVIDER: S-EPMC8630706 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature