Renal Prognosis in Children With Tubulointerstitial Nephritis and Uveitis Syndrome.

ABSTRACT:

Introduction

Tubulointerstitial nephritis (TIN) and uveitis (TINU) syndrome is a rare disease. The renal prognosis is generally thought to be better in children with TINU syndrome than in adults. However, data are scarce. We aimed to investigate the long-term renal prognosis in a French cohort of children with TINU syndrome.

Methods

We performed a national retrospective study including 23 French pediatric nephrology centers enrolling patients with TINU syndrome diagnosed between January 2000 and December 2018.

Results

A total of 46 patients were included (52% female, median age 13.8 years). At diagnosis of TIN, the median estimated glomerular filtration rate (eGFR) was 30.6 ml/min per 1.73 m² (4.9-62.8). The median time between diagnosis of uveitis and TIN

SUBMITTER: Chevalier A 

PROVIDER: S-EPMC8640547 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature