Whole Genome Sequencing identifies reciprocal translocation hT2(I;III) breakpoints.

ABSTRACT: We used whole-genome sequencing (WGS) data from a Caenorhabditis elegans strain homozygous for the reciprocal translocation hT2(I;III) to identify its breakpoints molecularly. The translocation structure is fairly straightforward, with only minor secondary rearrangement in addition to the primary breakpoints. The graphical representation below depicts the two hT2 half-translocations for ease of conceptualization.

SUBMITTER: Flibotte S 

PROVIDER: S-EPMC8662349 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature