Whole Genome Sequencing identifies reciprocal translocation hT2(I;III) breakpoints.
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ABSTRACT:
SUBMITTER: Flibotte S
PROVIDER: S-EPMC8662349 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Publications
Whole Genome Sequencing identifies reciprocal translocation <i>hT2(I;III)</i> breakpoints.
Flibotte Stephane S Edgley Mark M Au Vinci V Moerman Donald G DG
microPublication biology 20211209
We used whole-genome sequencing (WGS) data from a <i>Caenorhabditis elegans</i> strain homozygous for the reciprocal translocation <i>hT2(I;III)</i> to identify its breakpoints molecularly. The translocation structure is fairly straightforward, with only minor secondary rearrangement in addition to the primary breakpoints. The graphical representation below depicts the two <i>hT2</i> half-translocations for ease of conceptualization. ...[more]
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