Dataset Information

COVID-19 Outcomes Among US Military Health System Beneficiaries Include Complications Across Multiple Organ Systems and Substantial Functional Impairment.

ABSTRACT:

Background

We evaluated clinical outcomes, functional burden, and complications 1 month after coronavirus disease 2019 (COVID-19) infection in a prospective US Military Health System (MHS) cohort of active duty, retiree, and dependent populations using serial patient-reported outcome surveys and electronic medical record (EMR) review.

Methods

MHS beneficiaries presenting at 9 sites across the United States with a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) test, a COVID-19-like illness, or a high-risk SARS-CoV-2 exposure were eligible for enrollment. Medical history and clinical outcomes were collected through structured interviews and International Classification of Diseases-based EMR review. Risk factors associated with hospitalization were determined by multivariate logistic regression.

Results

A total of 1202 participants were enrolled. There were 1070 laboratory-confirmed SARS-CoV-2 cases and 132 SARS-CoV-2-negative participants. In the first month post-symptom onset among the SARS-CoV-2-positive cases, there were 212 hospitalizations, 80% requiring oxygen, 20 ICU admissions, and 10 deaths. Risk factors for COVID-19-associated hospitalization included race (increased for Asian, Black, and Hispanic compared with non-Hispanic White), age (age 45-64 and 65+ compared with <45), and obesity (BMI≥30 compared with BMI<30). Over 2% of survey respondents reported the need for supplemental oxygen, and 31% had not returned to normal daily activities at 1 month post-symptom onset.

Conclusions

Older age, reporting Asian, Black, or Hispanic race/ethnicity, and obesity are associated with SARS-CoV-2 hospitalization. A proportion of acute SARS-CoV-2 infections require long-term oxygen therapy; the impact of SARS-CoV-2 infection on short-term functional status was substantial. A significant number of MHS beneficiaries had not yet returned to normal activities by 1 month.

SUBMITTER: Richard SA

PROVIDER: S-EPMC8664684 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature

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COVID-19 Outcomes Among US Military Health System Beneficiaries Include Complications Across Multiple Organ Systems and Substantial Functional Impairment.

Richard Stephanie A SA Pollett Simon D SD Lanteri Charlotte A CA Millar Eugene V EV Fries Anthony C AC Maves Ryan C RC Utz Gregory C GC Lalani Tahaniyat T Smith Alfred A Mody Rupal M RM Ganesan Anuradha A Colombo Rhonda E RE Colombo Christopher J CJ Lindholm David A DA Madar Cristian C Chi Sharon S Huprikar Nikhil N Larson Derek T DT Bazan Samantha E SE English Caroline C Parmelee Edward E Mende Katrin K Laing Eric D ED Broder Christopher C CC Blair Paul W PW Chenoweth Josh G JG Simons Mark P MP Tribble David R DR Agan Brian K BK Burgess Timothy H TH

Open forum infectious diseases 20211110 12

<h4>Background</h4>We evaluated clinical outcomes, functional burden, and complications 1 month after coronavirus disease 2019 (COVID-19) infection in a prospective US Military Health System (MHS) cohort of active duty, retiree, and dependent populations using serial patient-reported outcome surveys and electronic medical record (EMR) review.<h4>Methods</h4>MHS beneficiaries presenting at 9 sites across the United States with a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 ...[more]

PMID: 34909439

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Dataset Information

COVID-19 Outcomes Among US Military Health System Beneficiaries Include Complications Across Multiple Organ Systems and Substantial Functional Impairment.

Background

Methods

Results

Conclusions

Publications

COVID-19 Outcomes Among US Military Health System Beneficiaries Include Complications Across Multiple Organ Systems and Substantial Functional Impairment.

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