Influenza Vaccine Effectiveness: Analysis of the Impact of Repeated Vaccinations in Military Health System Beneficiaries.

ABSTRACT:

Background

Influenza has long burdened the Military Health System (MHS). This study assesses the impact of repeated annual vaccination on influenza vaccine effectiveness (VE).

Methods

This retrospective, case control study using the test-negative design utilized data extracted from the MHS Data Repository (MDR). Cases had a positive influenza test and controls sought care for an influenza-like illness within 2 weeks of a case, had no positive influenza tests, and were matched by sex, race, age, and location. Vaccine effectiveness was assessed using conditional logistic regression separately for those who received inactivated and live attenuated influenza vaccines (LAIV).

Results

A total of 6860 cases and controls were identified in the MDR, among whom 53% were vaccina

SUBMITTER: Richard SA 

PROVIDER: S-EPMC9578161 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature