Chronic Hepatitis B Infection with Low Level Viremia Correlates with the Progression of the Liver Disease.

ABSTRACT:

Background and aims

Currently, insufficient clinical data are available to address whether low-level viremia (LLV) observed during antiviral treatment will adversely affect the clinical outcome or whether treatment strategies should be altered if LLV occurs. This study compared the clinical outcomes of patients with a maintained virological response (MVR) and patients who experienced LLV and their treatment strategies.

Methods

A retrospective cohort of 674 patients with chronic hepatitis B virus (HBV) infection who received antiviral treatment for more than 12 months was analyzed for the development of end-stage liver disease and treatment strategies during the follow-up period. End-stage liver disease included decompensated liver cirrhosis and hepatocellular carcinoma (HCC)

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC8666364 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature