Ontology highlight
ABSTRACT:
SUBMITTER: Liu CC
PROVIDER: S-EPMC8722024 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Liu Chi-Chun CC Shringarpure Suyash S Lange Kenneth K Novembre John J
Methods in molecular biology (Clifton, N.J.) 20200101
Population structure is a commonplace feature of genetic variation data, and it has importance in numerous application areas, including evolutionary genetics, conservation genetics, and human genetics. Understanding the structure in a sample is necessary before more sophisticated analyses are undertaken. Here we provide a protocol for running principal component analysis (PCA) and admixture proportion inference-two of the most commonly used approaches in describing population structure. Along wi ...[more]