Assessing the Impact of Acute Respiratory Illnesses on the Risk of Subsequent Respiratory Illness.

ABSTRACT:

Background

Whether acute respiratory illnesses (ARIs), often associated with virus detection, are associated with lower risk for subsequent ARI remains unclear. We assessed the association between symptomatic ARI and subsequent ARI in young children.

Methods

In a prospective cohort of Peruvian children <3 years, we examined the impact of index ARI on subsequent ARI risk. Index ARI were matched with ≤3 asymptomatic observations and followed over 28 days. We compared risk of subsequent ARI between groups using conditional logistic regression adjusting for several covariates, accounting for repeat observations from individual children.

Results

Among 983 index ARI, 339 (34%) had an ARI event during follow-up, compared with 876/2826 (31%) matched asymptomatic observations.

SUBMITTER: Howard LM 

PROVIDER: S-EPMC8730497 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature