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ABSTRACT: Background
The CHADS2, CHA2DS2-VASc, ATRIA, and Essen scores have been developed for predicting vascular outcomes in stroke patients. We investigated the association between these stroke risk scores and unsuccessful recanalization after endovascular thrombectomy (EVT).Methods
From the nationwide multicenter registry (Selection Criteria in Endovascular Thrombectomy and Thrombolytic therapy (SECRET)) (Clinicaltrials.gov NCT02964052), we consecutively included 501 patients who underwent EVT. We identified pre-admission stroke risk scores in each included patient.Results
Among 501 patients who underwent EVT, 410 (81.8%) patients achieved successful recanalization (mTICI ≥ 2b). Adjusting for body mass index and p < 0.1 in univariable analysis revealed the association between all stroke risk scores and unsuccessful recanalization (CHADS2 score: odds ratio (OR) 1.551, 95% confidence interval (CI) 1.198-2.009, p = 0.001; CHA2DS2VASc score: OR 1.269, 95% CI 1.080-1.492, p = 0.004; ATRIA score: OR 1.089, 95% CI 1.011-1.174, p = 0.024; and Essen score: OR 1.469, 95% CI 1.167-1.849, p = 0.001). The CHADS2 score had the highest AUC value and differed significantly only from the Essen score (AUC of CHADS2 score; 0.618, 95% CI 0.554-0.681).Conclusion
All stroke risk scores were associated with unsuccessful recanalization after EVT. Our study suggests that these stroke risk scores could be used to predict recanalization in stroke patients undergoing EVT.
SUBMITTER: Kim HJ
PROVIDER: S-EPMC8746082 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Kim Hyung Jun HJ Park Moo-Seok MS Yoo Joonsang J Kim Young Dae YD Park Hyungjong H Kim Byung Moon BM Bang Oh Young OY Kim Hyeon Chang HC Han Euna E Kim Dong Joon DJ Heo JoonNyung J Choi Jin Kyo JK Lee Kyung-Yul KY Lee Hye Sun HS Shin Dong Hoon DH Choi Hye-Yeon HY Sohn Sung-Il SI Hong Jeong-Ho JH Lee Jong Yun JY Baek Jang-Hyun JH Kim Gyu Sik GS Seo Woo-Keun WK Chung Jong-Won JW Kim Seo Hyun SH Han Sang Won SW Park Joong Hyun JH Kim Jinkwon J Jung Yo Han YH Cho Han-Jin HJ Ahn Seong Hwan SH Lee Sung Ik SI Seo Kwon-Duk KD Chang Yoonkyung Y Song Tae-Jin TJ Nam Hyo Suk HS
Journal of clinical medicine 20220105 1
<h4>Background</h4>The CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen scores have been developed for predicting vascular outcomes in stroke patients. We investigated the association between these stroke risk scores and unsuccessful recanalization after endovascular thrombectomy (EVT).<h4>Methods</h4>From the nationwide multicenter registry (Selection Criteria in Endovascular Thrombectomy and Thrombolytic therapy (SECRET)) (Clinicaltrials.gov NCT02964052), we consecutivel ...[more]