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Association between CHADS2, CHA2DS2-VASc, ATRIA, and Essen Stroke Risk Scores and Unsuccessful Recanalization after Endovascular Thrombectomy in Acute Ischemic Stroke Patients.


ABSTRACT:

Background

The CHADS2, CHA2DS2-VASc, ATRIA, and Essen scores have been developed for predicting vascular outcomes in stroke patients. We investigated the association between these stroke risk scores and unsuccessful recanalization after endovascular thrombectomy (EVT).

Methods

From the nationwide multicenter registry (Selection Criteria in Endovascular Thrombectomy and Thrombolytic therapy (SECRET)) (Clinicaltrials.gov NCT02964052), we consecutively included 501 patients who underwent EVT. We identified pre-admission stroke risk scores in each included patient.

Results

Among 501 patients who underwent EVT, 410 (81.8%) patients achieved successful recanalization (mTICI ≥ 2b). Adjusting for body mass index and p < 0.1 in univariable analysis revealed the association between all stroke risk scores and unsuccessful recanalization (CHADS2 score: odds ratio (OR) 1.551, 95% confidence interval (CI) 1.198-2.009, p = 0.001; CHA2DS2VASc score: OR 1.269, 95% CI 1.080-1.492, p = 0.004; ATRIA score: OR 1.089, 95% CI 1.011-1.174, p = 0.024; and Essen score: OR 1.469, 95% CI 1.167-1.849, p = 0.001). The CHADS2 score had the highest AUC value and differed significantly only from the Essen score (AUC of CHADS2 score; 0.618, 95% CI 0.554-0.681).

Conclusion

All stroke risk scores were associated with unsuccessful recanalization after EVT. Our study suggests that these stroke risk scores could be used to predict recanalization in stroke patients undergoing EVT.

SUBMITTER: Kim HJ 

PROVIDER: S-EPMC8746082 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature

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Publications

Association between CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen Stroke Risk Scores and Unsuccessful Recanalization after Endovascular Thrombectomy in Acute Ischemic Stroke Patients.

Kim Hyung Jun HJ   Park Moo-Seok MS   Yoo Joonsang J   Kim Young Dae YD   Park Hyungjong H   Kim Byung Moon BM   Bang Oh Young OY   Kim Hyeon Chang HC   Han Euna E   Kim Dong Joon DJ   Heo JoonNyung J   Choi Jin Kyo JK   Lee Kyung-Yul KY   Lee Hye Sun HS   Shin Dong Hoon DH   Choi Hye-Yeon HY   Sohn Sung-Il SI   Hong Jeong-Ho JH   Lee Jong Yun JY   Baek Jang-Hyun JH   Kim Gyu Sik GS   Seo Woo-Keun WK   Chung Jong-Won JW   Kim Seo Hyun SH   Han Sang Won SW   Park Joong Hyun JH   Kim Jinkwon J   Jung Yo Han YH   Cho Han-Jin HJ   Ahn Seong Hwan SH   Lee Sung Ik SI   Seo Kwon-Duk KD   Chang Yoonkyung Y   Song Tae-Jin TJ   Nam Hyo Suk HS  

Journal of clinical medicine 20220105 1


<h4>Background</h4>The CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen scores have been developed for predicting vascular outcomes in stroke patients. We investigated the association between these stroke risk scores and unsuccessful recanalization after endovascular thrombectomy (EVT).<h4>Methods</h4>From the nationwide multicenter registry (Selection Criteria in Endovascular Thrombectomy and Thrombolytic therapy (SECRET)) (Clinicaltrials.gov NCT02964052), we consecutivel  ...[more]

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