Factors Associated With Relapse and Treatment of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease in the United Kingdom.

ABSTRACT:

Importance

Longer-term outcomes and risk factors associated with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are not well established.

Objective

To investigate longer-term risk of relapse and factors associated with this risk among patients with MOGAD.

Design, setting, and participants

This large, single-nation, prospective cohort study was conducted among 276 patients with MOGAD at 5 health care centers in the UK. Data from January 1973 to March 2020 were collected from 146 patients at Oxford and its outreach sites, 65 patients at Liverpool, 32 patients at a children's hospital in Birmingham, 22 patients at a children's hospital in London, and 11 patients at Cardiff, Wales. Data were analyzed from April through July 2020.

Main outcomes

SUBMITTER: Satukijchai C 

PROVIDER: S-EPMC8749481 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature