Two-dimensional shear wave elastography predicts survival in advanced chronic liver disease.

ABSTRACT:

Objective

Liver stiffness measurement (LSM) is a tool used to screen for significant fibrosis and portal hypertension. The aim of this retrospective multicentre study was to develop an easy tool using LSM for clinical outcomes in advanced chronic liver disease (ACLD) patients.

Design

This international multicentre cohort study included a derivation ACLD patient cohort with valid two-dimensional shear wave elastography (2D-SWE) results. Clinical and laboratory parameters at baseline and during follow-up were recorded. LSM by transient elastography (TE) was also recorded if available. The primary outcome was overall mortality. The secondary outcome was the development of first/further decompensation.

Results

After screening 2148 patients (16 centres), 1827 patients (55

SUBMITTER: Trebicka J 

PROVIDER: S-EPMC8761995 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature