Magnetic resonance elastography for prediction of long-term progression and outcome in chronic liver disease: A retrospective study.

ABSTRACT:

Background and aims

Although magnetic resonance elastography (MRE) has been well-established for detecting and staging liver fibrosis, its prognostic role in determining outcomes of chronic liver disease (CLD) is mostly unknown.

Approach and results

This retrospective study consisted of 1269 subjects who underwent MRE between 2007 and 2009 and followed up until death or last known clinical encounter or end of study period. Charts were reviewed for cirrhosis development, decompensation, and transplant or death. The cohort was split into baseline noncirrhosis (group 1), compensated cirrhosis (group 2), and decompensated cirrhosis (group 3). Cox-regression analysis with age, sex, splenomegaly, CLD etiology, Child-Pugh Score (CPS), Fibrosis-4 Index (FIB-4) score, and Model for E

SUBMITTER: Gidener T 

PROVIDER: S-EPMC8766880 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature