Comparative Analysis of Three Trypanosomatid Catalases of Different Origin.
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ABSTRACT:
SUBMITTER: Chmelova L
PROVIDER: S-EPMC8773446 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Publications
Comparative Analysis of Three Trypanosomatid Catalases of Different Origin.
Chmelová Ľubomíra Ľ Bianchi Claretta C Albanaz Amanda T S ATS Režnarová Jana J Wheeler Richard R Kostygov Alexei Yu AY Kraeva Natalya N Yurchenko Vyacheslav V
Antioxidants (Basel, Switzerland) 20211226 1
Most trypanosomatid flagellates do not have catalase. In the evolution of this group, the gene encoding catalase has been independently acquired at least three times from three different bacterial groups. Here, we demonstrate that the catalase of <i>Vickermania</i> was obtained by horizontal gene transfer from Gammaproteobacteria, extending the list of known bacterial sources of this gene. Comparative biochemical analyses revealed that the enzymes of <i>V. ingenoplastis</i>, <i>Leptomonas pyrrho ...[more]
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