The Cost-Effectiveness of Surgical Intervention for Spinal Metastases: A Model-Based Evaluation.

ABSTRACT:

Background

Operative and nonoperative treatments for spinal metastases are expensive interventions with a high rate of complications. We sought to determine the cost-effectiveness of a surgical procedure compared with nonoperative management as treatment for spinal metastases.

Methods

We constructed a Markov state-transition model with health states defined by ambulatory status and estimated the quality-adjusted life-years (QALYs) and costs for operative and nonoperative management of spine metastases. We considered 2 populations: 1 in which patients presented with independent ambulatory status and 1 in which patients presented with nonambulatory status due to acute (e.g., <48 hours) metastatic epidural compression. We defined the efficacy of each treatment as a likelihood o

SUBMITTER: Schoenfeld AJ 

PROVIDER: S-EPMC8776911 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature