High prevalence of SARS-CoV-2 detection and prolonged viral shedding in stools: A systematic review and cohort study.

ABSTRACT:

Objectives

To: 1. Describe the frequency of viral RNA detection in stools in a cohort of patients infected with SARS-CoV-2, and 2. Perform a systematic review to assess the clearance time in stools of SARS-CoV-2.

Methods

We conducted a prospective cohort study in two centers between March and May 2020. We included SARS-CoV-2 infected patients of any age and severity. We collected seriated nasopharyngeal swabs and stool samples to detect SARS-CoV-2. After, we performed a systematic review of the prevalence and clearance of SARS-CoV-2 in stools (PROSPERO-ID: CRD42020192490). We estimated prevalence using a random-effects model. We assessed clearance time by using Kaplan-Meier curves.

Results

We included 32 patients; mean age was 43.7±17.7 years, 43.8% were female, and 4

SUBMITTER: Diaz LA 

PROVIDER: S-EPMC8783395 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature