Clinical metagenomic sequencing for rapid diagnosis of neonatal meningitis caused by Ureaplasma parvum: A case report.

ABSTRACT:

Introduction

It is challenging to obtain favorable results through conventional diagnostic testing for Ureaplasma parvum (UP), a conditional pathogen, because of the atypical clinical phenotype of UP meningitis.

Patient concerns and diagnosis

Herein, we report a pediatric case of neonatal meningitis caused by UP in a spontaneously delivered full-term baby. The infant's temperature peak was 38.3°C at the age of 9 days. The patient was diagnosed with neonatal suppurative meningitis.

Interventions and outcomes

The pathogen was diagnosed in a timely and accurate manner by metagenome sequencing, and the patient was eventually discharged with azithromycin.

Conclusions

Neonatal Ureaplasma meningitis may be more common than previously suspected. The clinical manifestat

SUBMITTER: Qin L 

PROVIDER: S-EPMC8797581 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature