A platform for oncogenomic reporting and interpretation.
Ontology highlight
ABSTRACT:
SUBMITTER: Reisle C
PROVIDER: S-EPMC8828759 | biostudies-literature | 2022 Feb
REPOSITORIES: biostudies-literature
Publications
A platform for oncogenomic reporting and interpretation.
Reisle Caralyn C Williamson Laura M LM Pleasance Erin E Davies Anna A Pellegrini Brayden B Bleile Dustin W DW Mungall Karen L KL Chuah Eric E Jones Martin R MR Ma Yussanne Y Lewis Eleanor E Beckie Isaac I Pham David D Matiello Pletz Raphael R Muhammadzadeh Amir A Pierce Brandon M BM Li Jacky J Stevenson Ross R Wong Hansen H Bailey Lance L Reisle Abbey A Douglas Matthew M Bonakdar Melika M Nelson Jessica M T JMT Grisdale Cameron J CJ Krzywinski Martin M Fisic Ana A Mitchell Teresa T Renouf Daniel J DJ Yip Stephen S Laskin Janessa J Marra Marco A MA Jones Steven J M SJM
Nature communications 20220209 1
Manual interpretation of variants remains rate limiting in precision oncology. The increasing scale and complexity of molecular data generated from comprehensive sequencing of cancer samples requires advanced interpretative platforms as precision oncology expands beyond individual patients to entire populations. To address this unmet need, we introduce a Platform for Oncogenomic Reporting and Interpretation (PORI), comprising an analytic framework that facilitates the interpretation and reportin ...[more]
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