Identification of Prognostic lncRNA Related to the Immune Microenvironment of Soft Tissue Sarcoma.

ABSTRACT:

Background

Soft tissue sarcoma is a malignant tumor with high degree of malignancy and poor prognosis, originating from mesenchymal tissue. Long noncoding RNAs (lncRNAs) are involved in various biological and pathological processes in the body. They perform preprocessing, splicing, transport, degradation, and translation of mRNA to achieve posttranscriptional level regulation, resulting in the occurrence, invasion, and metastasis of tumors. Therefore, they are highly relevant with regard to early diagnoses and as prognostic indicators.

Objective

The objective of the present study was to identify immune microenvironment-related lncRNAs that can be used to predict soft tissue sarcomas.

Methods

Clinical data and follow-up data were obtained from the cBioPortal database,

SUBMITTER: Dai WY 

PROVIDER: S-EPMC8832153 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature