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Structure, Function and Regulation of the Plasma Membrane Calcium Pump in Health and Disease.

ABSTRACT: In this review, I summarize the present knowledge of the structural and functional properties of the mammalian plasma membrane calcium pump (PMCA). It is outlined how the cellular expression of the different spliced isoforms of the four genes are regulated under normal and pathological conditions.

SUBMITTER: Krebs J 

PROVIDER: S-EPMC8835232 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature

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Structure, Function and Regulation of the Plasma Membrane Calcium Pump in Health and Disease.

Krebs Joachim J  

International journal of molecular sciences 20220118 3

In this review, I summarize the present knowledge of the structural and functional properties of the mammalian plasma membrane calcium pump (PMCA). It is outlined how the cellular expression of the different spliced isoforms of the four genes are regulated under normal and pathological conditions. ...[more]

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