Postnatal exposure to PM_2.5 and weight trajectories in early childhood.

ABSTRACT:

Background

Inconsistent evidence has assessed the impact of air pollution exposure on children's growth trajectories. We investigated the role of 90-day average postnatal fine particulate matter (PM_2.5) exposures by estimating the magnitude of effects at different ages, and the change in child weight trajectory by categories of exposure.

Methods

We obtained weight values from electronic health records at each hospital visit (males = 1859, females = 1601) from birth to 6 years old children recruited into the Boston-based Children's HealthWatch cohort (2009-2014). We applied mixed models, adjusting for individual and maternal confounders using (1) varying-coefficient models allowing for smooth non-linear interaction between age and PM_2.5, (2) factor-smoot

SUBMITTER: Vanoli J 

PROVIDER: S-EPMC8835545 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature