Molecular docking studies of phytochemicals from Terminalia chebula for identification of potential multi-target inhibitors of SARS-CoV-2 proteins.

ABSTRACT:

Background

The COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged as a global pandemic claiming more than 6 million lives worldwide as of 16 March 2022. Till date, no medicine has been developed which is proved to have 100% efficiency in combating against this deadly disease. We focussed on ayurvedic medicines to identify drug-like candidates for treatment and management of COVID-19. Among all ayurvedic medicines, we were interested in Terminalia chebula (T. chebula), as it is known to have antibacterial, antifungal, antiviral, antioxidant and anti-inflammatory properties.

Objectives

In this study, we evaluated potential inhibitory effects of phytochemicals from T. chebula against eight structural and functional proteins

SUBMITTER: Sarkar A 

PROVIDER: S-EPMC8847108 | biostudies-literature | 2022 Apr-Jun

REPOSITORIES: biostudies-literature