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Decreasing delivery room CPAP-associated pneumothorax at ≥35-week gestational age.


ABSTRACT:

Objective

We previously reported an increase in pneumothorax after implementing delivery room (DR) continuous positive airway pressure (CPAP) for labored breathing or persistent cyanosis in ≥35-week gestational age (GA) neonates unexposed to DR-positive pressure ventilation (DR-PPV). We hypothesized that pneumothorax would decrease after de-implementing DR-CPAP in those unexposed to DR-PPV or DR-O2 supplementation (DR-PPV/O2).

Study design

In a retrospective cohort excluding DR-PPV the primary outcome was DR-CPAP-related pneumothorax (1st chest radiogram, 1st day of life). In a subgroup treated by the resuscitation team and admitted to the NICU, the primary outcome was DR-CPAP-associated pneumothorax (1st radiogram, no prior PPV) without DR-PPV/O2.

Results

In the full cohort, occurrence of DR-CPAP-related pneumothorax decreased after the intervention (11.0% vs 6.0%, P < 0.001). In the subgroup, occurrence of DR-CPAP-associated pneumothorax decreased after the intervention (1.4% vs. 0.06%, P < 0.001).

Conclusion

The occurrence of CPAP-associated pneumothorax decreased after avoiding DR-CPAP in ≥35-week GA neonates without DR-PPV/O2.

SUBMITTER: Stocks EF 

PROVIDER: S-EPMC8853308 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature

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Publications

Decreasing delivery room CPAP-associated pneumothorax at ≥35-week gestational age.

Stocks Edward F EF   Jaleel Mambarambath M   Smithhart William W   Burchfield Patti J PJ   Thomas Anita A   Mangona Kate Louise M KLM   Kapadia Vishal V   Wyckoff Myra M   Kakkilaya Venkatakrishna V   Brenan Shelby S   Brown L Steven LS   Clark Christopher C   Nelson David B DB   Brion Luc P LP  

Journal of perinatology : official journal of the California Perinatal Association 20220216 6


<h4>Objective</h4>We previously reported an increase in pneumothorax after implementing delivery room (DR) continuous positive airway pressure (CPAP) for labored breathing or persistent cyanosis in ≥35-week gestational age (GA) neonates unexposed to DR-positive pressure ventilation (DR-PPV). We hypothesized that pneumothorax would decrease after de-implementing DR-CPAP in those unexposed to DR-PPV or DR-O<sub>2</sub> supplementation (DR-PPV/O<sub>2</sub>).<h4>Study design</h4>In a retrospective  ...[more]

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