A plasma fatty acid profile associated to type 2 diabetes development: from the CORDIOPREV study.

ABSTRACT:

Purpose

The prevalence of type 2 diabetes mellitus (T2DM) is increasing worldwide. For this reason, it is essential to identify biomarkers for the early detection of T2DM risk and/or for a better prognosis of T2DM. We aimed to identify a plasma fatty acid (FA) profile associated with T2DM development.

Methods

We included 462 coronary heart disease patients from the CORDIOPREV study without T2DM at baseline. Of these, 107 patients developed T2DM according to the American Diabetes Association (ADA) diagnosis criteria after a median follow-up of 60 months. We performed a random classification of patients in a training set, used to build a FA Score, and a Validation set, in which we tested the FA Score.

Results

FA selection with the highest prediction power was performed

SUBMITTER: Villasanta-Gonzalez A 

PROVIDER: S-EPMC8854256 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature