Prevalence of Ocular Anomalies in Craniosynostosis: A Systematic Review and Meta-Analysis.

ABSTRACT: The aim of this study was to describe the ophthalmic abnormalities and their prevalence in craniosynostosis prior to craniofacial surgery. A systematic search was conducted on Medline OVID, Embase, Cochrane, Google Scholar, Web of Science Core Collection. Inclusion criteria were English papers, children aged <18 years with non-syndromic and syndromic craniosynostosis, case reports, case series, and case-control studies. A system of domains was established consisting of an anatomic and functional ophthalmic domain. A meta-analysis of single proportions was carried out using random effects model and pooled mean proportions with 95% confidence intervals (CI) were calculated. Thirty-two papers analyzing 2027 patients were included. Strabismus was the most common anomaly in non-syndromic cranio

SUBMITTER: Rostamzad P 

PROVIDER: S-EPMC8877705 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature