Etiology of severe invasive infections in young infants in rural settings in sub-Saharan Africa.

ABSTRACT:

Background

Serious invasive infections in newborns are a major cause of death. Lack of data on etiological causes hampers progress towards reduction of mortality. This study aimed to identify pathogens responsible for such infections in young infants in sub-Saharan Africa and to describe their antibiotics resistance profile.

Methods

Between September 2016 and April 2018 we implemented an observational study in two rural sites in Burkina Faso and Tanzania enrolling young infants aged 0-59 days old with serious invasive infection. Blood samples underwent blood culture and molecular biology.

Results

In total 634 infants with clinical diagnosis of serious invasive infection were enrolled and 4.2% of the infants had a positive blood culture. The most frequent pathogens ide

SUBMITTER: Mduma E 

PROVIDER: S-EPMC8880396 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature