Psychedelic use is associated with reduced daily opioid use among people who use illicit drugs in a Canadian setting.

ABSTRACT:

Background

Research into the therapeutic and naturalistic uses of psychedelics for improving outcomes related to mental health disorders has generated increasing interest in recent years. While controlled clinical trials of psychedelics have signaled benefits for treating substance use disorders, this area has not been well studied in the context of naturalistic psychedelic use. This study sought to investigate the possible relationship between recent naturalistic psychedelic use and subsequent daily illicit opioid use among people who use drugs (PWUD).

Methods

Data (2006-2018) were drawn from three harmonized prospective cohorts of community-recruited PWUD in Vancouver, Canada. We used multivariable generalized linear mixed-effects modeling (GLMM) to estimate the independen

SUBMITTER: Argento E 

PROVIDER: S-EPMC8890776 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature