Feasibility of Using Daily Home High-Flow Nasal Therapy in COPD Patients Following a Recent COPD Hospitalization.

ABSTRACT:

Rationale

High-flow nasal therapy (HFNT) has beneficial effects in patients hospitalized with acute hypoxemic respiratory failure. HFNT has not been extensively studied following hospitalization for an acute exacerbation of chronic obstructive pulmonary disease (AECOPD).

Objective

We explored the feasibility of conducting a multicentered trial to evaluate the use of HFNT to increase the time to next moderate/ severe exacerbation in patients recently hospitalized for a COPD exacerbation. In this pilot study we measured the hours of home daily HFNT use, maximally tolerated flow rates and temperature, and side effects for a period of 90 days.

Methods

Patients were enrolled in a 90-day, open-labeled pilot study of HFNT to determine the safety and feasibility of home use f

SUBMITTER: Criner GJ 

PROVIDER: S-EPMC8893969 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature