Spotlight on MuSK positive myasthenia gravis: clinical characteristics, treatment and outcomes.

ABSTRACT:

Background

To investigate the clinical characteristics, treatments and outcomes of patients with myasthenia gravis with antibodies to muscle-specific tyrosine kinase (MuSK-MG).

Methods

We retrospectively reviewed the cases of 21 patients with confirmed MuSK-MG between January 2012 and January 2020 in our centre. Detailed clinical data and long-term follow-up information were summarized.

Results

Females (17/21, 81%) predominated among these MuSK-MG patients, and the mean age of onset in this group was 51.86 ± 16.16 years. MuSK-MG patients were divided into three subgroups according to the symptoms of muscle weakness at onset: ocular myasthenia gravis (OMG, 47.6%), bulbar myasthenia gravis (BMG, 42.9%), and generalized myasthenia gravis (GMG, 9.5%). The mean progression

SUBMITTER: Huang Q 

PROVIDER: S-EPMC8895578 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature