Burden of whooping cough in China (PertussisChina): study protocol of a prospective, population-based case-control study.

ABSTRACT:

Introduction

Pertussis is one of the top 10 diseases of children under 10 years of age, and the few vaccine-preventable diseases who is on a rise in China in recent years; however, the true burden of pertussis, including age-stratified incidence and risk factors of severe sequelae, are under-recognised. We aim to estimate the health burden of laboratory-confirmed pertussis by age groups, considering the setting of illness onset (ie, in community, outpatient and inpatient), in a Chinese population (~2.23 million in total) at two sites.

Methods and analysis

This paper describes the study design of a 1-year, prospective, age-stratified and population-based case-control study, including site selection, study population, case registry, ascertainment and enrolment, control recruit

SUBMITTER: Yu J 

PROVIDER: S-EPMC8915282 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature