Advances in Liver Transplantation for Persons with Human Immunodeficiency Infection.

ABSTRACT:

Purpose of review

Advanced liver disease is a leading cause of non-AIDS-related morbidity and mortality in persons with HIV on antiretroviral therapy. As a result, persons with HIV are increasingly seeking liver transplantation.

Recent findings

With the availability of direct-acting antiviral hepatitis C therapies, there has been a shift in the indications for liver transplantation in persons with HIV, with non-alcoholic fatty liver disease now the leading indication over hepatitis C infection. Additionally, liver transplant outcomes have improved in persons with HIV-hepatitis C co-infection persons with HIV. Preliminary results of HIV-to-HIV liver transplantation show acceptable results although rates of post-transplant infections and malignancies are areas of concern.

S

SUBMITTER: Kumar RN 

PROVIDER: S-EPMC8922075 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature