Boosters reduce in-hospital mortality in patients with COVID-19: An observational cohort analysis.

ABSTRACT:

Background

Real-world data on the effectiveness of boosters against COVID-19, especially as new variants continue to emerge, is limited. Our objective was to assess demographic, clinical, and outcome variables of patients requiring hospitalization for severe SARS-CoV-2 infection comparing fully vaccinated and boosted (FV&B), fully vaccinated (FV), and unvaccinated (UV) patients.

Methods

This multicenter observational cohort analysis compared demographic, clinical, and outcome variables in FV&B, FV, and UV adults hospitalized for COVID-19. Partially vaccinated (PV) and individuals still hospitalized beyond the designated follow-up date of February 1, 2022 were excluded. The primary endpoint was in-hospital mortality. Secondary endpoints included characteristics and outcomes i

SUBMITTER: Mielke N 

PROVIDER: S-EPMC8926847 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature