Development of spray-drying-based surface-enhanced Raman spectroscopy.

ABSTRACT: We report a spray-drying method to fabricate silver nanoparticle (AgNP) aggregates for application in surface-enhanced Raman spectroscopy (SERS). A custom-built system was used to fabricate AgNP aggregates of four sizes, 48, 86, 151, and 218 nm, from drying droplets containing AgNPs atomized from an AgNP suspension. Sample solutions of Rhodamine B (RhB) at 10^-6, 10^-8, and 10^-10 M concentrations were dropped onto the AgNP aggregates as probe molecules to examine the enhancement of the Raman signals of the RhB. The ordering of the analytical enhancement factors (AEFs) by aggregate size at a 10^-6 M RhB was 86 nm > 218 nm > 151 nm > 48 nm. When RhB concentrations are below 10^-8 M, the 86 and 151 nm AgNP aggregates show clear RhB peaks. The

SUBMITTER: Matsumoto C 

PROVIDER: S-EPMC8927375 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature