Structural and Functional Characterization of a Novel Recombinant Antimicrobial Peptide from Hermetia illucens.

ABSTRACT: Antibiotics are commonly used to treat pathogenic bacteria, but their prolonged use contributes to the development and spread of drug-resistant microorganisms raising the challenge to find new alternative drugs. Antimicrobial peptides (AMPs) are small/medium molecules ranging 10-60 residues synthesized by all living organisms and playing important roles in the defense systems. These features, together with the inability of microorganisms to develop resistance against the majority of AMPs, suggest that these molecules might represent effective alternatives to classical antibiotics. Because of their high biodiversity, with over one million described species, and their ability to live in hostile environments, insects represent the largest source of these molecules. However, production of inse

SUBMITTER: Di Somma A 

PROVIDER: S-EPMC8929087 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature