Duration of infectious viral shedding in patients with mild to moderate COVID-19 treated with REGN-CoV2.

ABSTRACT:

Introduction

New treatment methods, such as REGN-CoV2, have been approved for patients with coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the effect of the drug on the duration of infectious viral shedding and viral mutations is unknown. In this study, we investigated the clinical efficacy of REGN-CoV2 treatment in patients with mild to moderate disease and compared its antiviral effects against different strains of SARS-CoV-2.

Methods

Viral culture and PCR testing were performed on the pharyngeal swabs collected from 28 patients with COVID-19 who were admitted and treated at Hiroshima University Hospital during the study period. Of these, 23 patients were treated with REGN-CoV2. The patients were classified i

SUBMITTER: Nomura T 

PROVIDER: S-EPMC8938179 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature