A conditional GABAergic synaptic vesicle marker for Drosophila.

ABSTRACT:

Background

Throughout the animal kingdom, GABA is the principal inhibitory neurotransmitter of the nervous system. It is essential for maintaining the homeostatic balance between excitation and inhibition required for the brain to operate normally. Identification of GABAergic neurons and their GABA release sites are thus essential for understanding how the brain regulates the excitability of neurons and the activity of neural circuits responsible for numerous aspects of brain function including information processing, locomotion, learning, memory, and synaptic plasticity, among others.

New method

Since the structure and features of GABA synapses are critical to understanding their function within specific neural circuits of interest, here we developed and characterized a con

SUBMITTER: Certel SJ 

PROVIDER: S-EPMC8940707 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature